The Goodlett Laboratory
David Goodlett
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David Goodlett
Professor and Isaac E. Emerson Chair of Pharmaceutical Sciences
Since 2013 David R Goodlett has been the Isaac E. Emerson Professor of Pharmaceutical Sciences at the University of Maryland School of Pharmacy. From 2013-2015 he was Director of the UMB School of Pharmacy MS Center. In 2012 he began a four & a half year tenure as a Finland Distinguished Professor (FiDiPro) at the University of Turku. The research at the University of Turku has been focused on discovery of serum protein markers that predict children who will develop type-1 diabetes prior to appearance of autoantibodies as well as cardiovascular disease in young Finns. More details of the FiDiPro projects are available here.

From 2004-2012 he was Professor of Medicinal Chemistry at the University of Washington where he was also Director of the School of Pharmacy mass spectrometry facility. His research includes hypothesis generating, discovery based efforts in protein and lipid A structure-function relationships in infectious organisms, proteomics technology development and informatics. Prior to his nine-year term at the University of Washington, he was Director of the Institute for Systems Biology™ Proteomics laboratory (2000-2003). After postdoctoral work with Richard D. Smith at Pacific Northwest National Laboratory (1991-1993), he spent five years in the pharmaceutical industry and prior to that received his Ph.D. in 1991 with Richard B. van Breemen and Frank B. Armstrong (deceased) at North Carolina State University.

Originally, he was trained as a protein chemist at Auburn University with John Aull, Harlow Daron (deceased) and Frank Bartol. This training in structure-function relationships led to an eventual interest in the same concept for lipid A as it pertains to human health that he has investigated using mass spectrometry. His current efforts are supported by several burgeoning technology projects in mass spectrometry and microfluidics, as well as software development to support structure analysis and –omic pipelines. The discovery based science projects within the laboratory are used to generate hypotheses complementary to those generated by literature review in support of our medical and biological collaborators. In general, we take an indolent driven approach to experimentation that seeks parsimony in data acquisition and interpretation.

phone: 206-616-4686
Lisa Leung
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Lisa Leung
Graduate Student

phone: 410.706.3536
Shivangi Awasthi
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Shivangi Awasthi
Graduate Student, Department of Pharmaceutical Sciences

phone: 410.706.3536
Mohsin Kahn
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Mohsin Kahn
Graduate Student

Ben Oyler
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Ben Oyler
Graduate Student, Pharmaceutical Sciences

Sung Hwan Yoon
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Sung Hwan Yoon
Postdoctoral Fellow

phone: 410.706.3536
Tao Liang
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Tao Liang
Graduate Student

phone: 410.706.3536
Will Fondrie
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Will Fondrie
Graduate Student
My dissertation project investigates the tumor suppressor functions of the low-density lipoprotein receptor-related protein 1B (LRP1B) in glioblastoma using modern proteomics, sequencing and molecular biology methods. My first research experience was in the laboratory of Dr. John Papanikolas studying materials for dye-sensitized solar cells with ultrafast spectroscopy technique. However I quickly realized that while I was fully engaged in research, I was not invested in the topic solar energy. Instead I saw the opportunity to use my analytical skills and biochemistry education to improve cancer treatment and diagnosis. For my graduate education, I chose to pursue the Genome Biology track in the Molecular Medicine PhD program at the University Of Maryland School of Medicine so that I would be well prepared to perform ‘omics research in cancer biology. My initial graduate research experience was in the laboratory of Dr. Austin Yang to investigate the proteome of cancer exosomes using mass spectrometry. While rotating in his laboratory, I was introduced to bottom-up proteomics through mass spectrometry and the statistical analysis of proteomics data. This included an introduction to machine learning techniques and the R programming language. To complete my thesis research, I’ve joined the laboratories of Dr. Dudley Strickland and Dr. David Goodlett where I am investigating the tumor suppressor mechanism of the low-density lipoprotein receptor-related protein 1B (LRP1B) largely through proteomics. Dr. Strickland leads one of the two laboratories that discovered LRP1, the closest homologue to LRP1B, and his laboratory currently focuses on different aspects of LRP1 research. Likewise, Dr. Goodlett is one of the leading researchers in biological mass spectrometry and proteomics. See more about me here

Saddef Haq
Saddef Haq
Graduate Student

Young Ah Goo
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Young Ah Goo
Research Assistant Professor
Young Ah Goo joined the Department of Pharmaceutical Sciences (PSC) as a research assistant professor and an associate director of the Mass Spectrometry Center in 2013. Her research focuses on use of mass spectrometry-based proteomics applications to study biological questions, applying global systems approaches with focus towards the discovery of diagnostic/prognostic biomarkers and therapeutic targets for human diseases. Prior to joining the PSC, she was a clinical assistant professor in the School of Nursing at the University of Washington (UW) in Seattle, where her research focused on study of chronic pain syndromes, including interstitial cystitis, HIV/AIDS fatigue syndrome, and irritable bowel syndrome. She conducted her post-doctoral fellowship at the Institute for Systems Biology, where she worked in the prostate cancer research group and the proteomics group affiliated with Drs. David Goodlett and Ruedi Aebersold. She earned her PhD in genome sciences/pathobiology with Dr. Leroy Hood at UW, where she gained expertise in functional genomics employing microarray based transcriptome analysis, cloning, and sequencing. Her training expanded into proteomics using mass spectrometry and ultimately adopting systems biology approach studying the complex mechanisms of Archaeal Extremophiles during her PhD.

phone: 410.706.3380
Bao Tran
Bao Tran
Post Doctoral Fellow

Michael Wilson
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Michael Wilson
IT Analyst

Graham Goodlett
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Graham Goodlett
Intern

phone: 410.706.3536
Alex Scherl
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Alex Scherl
Univ. of Geneva Proteomics Core Facility and Biomedical Proteomics Research Group

Brendan Ribera
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Brendan Ribera
Unknown
My name is Brendan Ribera. I live in Seattle with my wife and kids, where we are members of Green Lake Presbyterian Church. I create software. I enjoy art, literature, music, startups, theology, hacking, baking, mathematics, open-source software, bicycling, backpacking, et cetera.

Byron Gallis
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Byron Gallis
Research Scientist

Eric Foss
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Eric Foss
Staff Scientist FHCRC

Greg Taylor
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Greg Taylor
Graduate Student, Molecular and Cellular Biology

Jason Shaw
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Jason Shaw
Unknown

Jocelyn Setter
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Jocelyn Setter
Coordinator of MS-based experiments, Seattle Genetics

Karl-Henning Kalland
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Karl-Henning Kalland
Visiting Professor, University of Bergen

Manhong Wu
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Manhong Wu
Research Associate, Stanford University School of Medicine

Yu-Chieh (Philip) Kao
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Yu-Chieh (Philip) Kao
Visting Scientist

Pragya Singh
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Pragya Singh
Postdoctoral Fellow, Lawrence Berkeley National Laboratory

Scott Edgar
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Scott Edgar
Research Associate

Yi-Hsuan (Shannon) Tsai
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Yi-Hsuan (Shannon) Tsai
Graduate Student, BIological and Biomadeical Sciences, North Caolina

Shuhua Chen
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Shuhua Chen
Graduate Student, Chemistry, Texas A&M

Soyoung Ryu
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Soyoung Ryu
Postdoctoral Fellow, Stanford University

Thao (Jenny) To
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Thao (Jenny) To
Graduate Student, Oral Biology

Thomas Schneider
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Thomas Schneider
Research Associate
University of Washington,
Department of Chemistry

David P. A. Kilgour
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David P. A. Kilgour
His Excellency

phone: 410.706.5582
Scott Heron
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Scott Heron
Research Associate

phone: 410.706.3536
Lucas Monkkonen
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Lucas Monkkonen
Graduate Student

phone: 410.706.3536
Alex Panchaud
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Alex Panchaud
Associate R&D Specialist, Nestléesearch Center

Anne M. Oyan
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Anne M. Oyan
Visiting Scholar, University of Bergen

Brook Nunn
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Brook Nunn
Research Scientist

Catalin Doneanu
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Catalin Doneanu
Sebuir Research Chemist, Waters Corporation

Chan Chun(Eric) Yong
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Chan Chun(Eric) Yong
Visiting Scholar, Associate Professor, Department of Pharmacy, University of Singapore

Jace Jones
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Jace Jones
Laborator Research Manager, Department of Pharmaceutical Sciences UMB

Jinzhi Chen
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Jinzhi Chen
Takeda Pharmaceuticals (Research Associate)

Jon Chapman
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Jon Chapman
Graduate Student, Medicinal Chemistry

Lars Mamstroem
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Lars Mamstroem
Institute of Molecular Systems Biology, ETH Zurich

Mimi Nguyen
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Mimi Nguyen
Student

Daniel Powell
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Daniel Powell
Student

Sandy Yates
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Sandy Yates
Product Specialist/Small Molecules, Bruker Daltonics

Scott Shaffer
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Scott Shaffer
Univ. of Massachusetts Medical School

Shawna Hengel
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Shawna Hengel
Scientist, Bioanlytical Development Seattle Genetics, Inc.

Ying (Sonia) Ting
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Ying (Sonia) Ting
Graduate Student, Genome Sciences, UW

Sunhee Jung
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Sunhee Jung
Research Scientist III, Seattle Children's Research Institute

Yue Huang
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Yue Huang
Graduate Student, Chemistry

Alison Scott
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Alison Scott
Postdoctoral Fellow

Adelina Ascosta Martin
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Adelina Ascosta Martin
Visiting Scientist

Dasongh Hua
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Dasongh Hua
Visiting Scientist

Jie Liu
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Jie Liu
Visiting Scientist

Laura Collantes de Teran
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Laura Collantes de Teran
Visiting Scientist

Bob Hommersom
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Bob Hommersom
Graduate Student, Chemistry - AMOLF

Christophe Masselon
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Christophe Masselon
Visiting Scientist

Ivanka Karadzic
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Ivanka Karadzic
Visiting Scientist

Jie (Jessie) Xing
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Jie (Jessie) Xing
Visiting Scientist

Xuenfeng Fung
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Xuenfeng Fung
Visiting Scientist

Tanzila Rehman
Tanzila Rehman
Lecturer
The Women University Multan,
Department of Chemistry,
Pakistan

phone: 92.332.061.6379
Antonio Bedalov
Antonio Bedalov
Fred Hutchinson Cancer Research Center

Pat Langridge-Smith
Pat Langridge-Smith
University of Edinburgh

Robert K. Ernst
Robert K. Ernst
University of Maryland Dental School

phone: 410.706.2263
Victor Ng
Victor Ng
Institute of Biotechnology and Institute of Bioinformatics, National Yang Ming University